Fcgr2 CLIA Kit for Mouse(Mus musculus) | EIAab.comFcgr2 CLIA Kit for Mouse(Mus musculus)

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Fcgr2 (Gene name),

Low affinity immunoglobulin gamma Fc region receptor II (Protein name ), FCGR2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Fcgr2(Fcgr2b;Ly-17);

Protein name:

Low affinity immunoglobulin gamma Fc region receptor II;

Alternative:

IgG Fc receptor II beta;Fc gamma receptor IIB(Fc-gamma RII;Fc-gamma-RIIB;FcRII);Lymphocyte antigen 17(Ly-17);

CD:

CD32;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with FGR.

Function:

Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of antigen-antibody complexes from the circulation and modulation of antibody production by B-cells. Isoform IIB1 and isoform IIB1' form caps but fail to mediate endocytosis or phagocytosis. Isoform IIB2 can mediate the endocytosis of soluble immune complexes via clathrin-coated pits. Isoform IIB1 and isoform IIB2 can down-regulate B-cell, T-cell, and mast cell activation when coaggregated to B-cell receptors for AG (BCR), T-cell receptors for AG (TCR), and Fc receptors, respectively.

Subcellular Location:

Isoform IIB3 Secreted Released as a soluble molecule.

Protein Attributes:

Sequence length:

330

Sequence:

50:

100:

150:

200:

250:

300:

330:

TEAENTITYS | LLKHPEALDE | ETEHDYQNHI |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.425062

SMR:

P08101

STRING:

10090.ENSMUSP00000027966

KEGG:

mmu:14130

String:

P08101

Uniprot:

P08101

FOR

ELISA Kit for Mouse Low affinity immunoglobulin gamma Fc region receptor II

Cat.:

E1579b

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96T

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ELISA Kit for Mouse Low affinity immunoglobulin gamma Fc region receptor II

Cat.:

E1579m

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96T

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ELISA Kit for Mouse Low affinity immunoglobulin gamma Fc region receptor II

Cat.:

E1579r

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Packing:

96T

CLIA Kit for Mouse Low affinity immunoglobulin gamma Fc region receptor II

Cat.:

U1579b

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Low affinity immunoglobulin gamma Fc region receptor II

Cat.:

U1579r

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Low affinity immunoglobulin gamma Fc region receptor II

Cat.:

U1579m

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96T

Polyclonal Antibody for Mouse Low affinity immunoglobulin gamma Fc region receptor II

Cat.:

P1579Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse Low affinity immunoglobulin gamma Fc region receptor II

Cat.:

P1579Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Low affinity immunoglobulin gamma Fc region receptor II

Monoclonal Antibody for Mouse Low affinity immunoglobulin gamma Fc region receptor II

Protein for Mouse Low affinity immunoglobulin gamma Fc region receptor II

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Structural heterogeneity and functional domains of murine immunoglobulin G Fc receptors."
Ravetch J.V. , Luster A.D. , Weinshank R. , Kochan J. , Pavlovec A. , Portnoy D.A. , Hulmes J. , Pan Y.-C.E. , Unkeless J.C.
Science234:718-725(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 30-51 (ISOFORMS IIB1 AND IIB2)
2.

"A complementary DNA clone for a macrophage-lymphocyte Fc receptor."
Lewis V.A. , Koch T. , Plutner H. , Mellman I.
Nature324:372-375(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM IIB2)
tissue: Macrophage.
3.

"The mouse Fc receptor for IgG (Ly-17): molecular cloning and specificity."
Hogarth P.M. , Hibbs M.L. , Bonadonna L. , Scott B.M. , Witort E. , Pietersz G.A. , McKenzie I.F.C.
Immunogenetics26:161-168(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE (ISOFORM IIB1)
4.

"Identification of the mouse beta Fc gamma RII polymorphism by direct sequencing of amplified genomic DNA."
Lah M. , Quelch K. , Deacon N.J. , McKenzie I.F. , Hogarth P.M.
Immunogenetics31:202-206(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM IIB1);VARIANTS
strain: BALB/c.
tissue: Spleen.
5.

"Structure of the mouse beta Fc gamma receptor II gene."
Hogarth P.M. , Witort E. , Hulett M.D. , Bonnerot C. , Even J. , Fridman W.H. , McKenzie I.F.C.
J. Immunol.146:369-376(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ISOFORMS IIB1 AND IIB2)
6.

"Identification, molecular cloning, biologic properties, and tissue distribution of a novel isoform of murine low-affinity IgG receptor homologous to human Fc gamma RIIB1."
Latour S. , Fridman W.H. , Daeron M.
J. Immunol.157:189-197(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM IIB1')
strain: DBA/2.
tissue: Mast cell.
7.

"Nonsynonymous mutations in an Fc-receptor structural gene in NZB mice."
Sawchuk D.J. , Mahmoudi M. , Cairns E. , Sinclair N.R.S.
Immunogenetics43:112-113(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 30-330 (ISOFORMS IIB1 AND IIB2)
strain: DBA/2.
strain: NZB.
tissue: Spleen.
8.

"The murine Fc receptor for immunoglobulin: purification, partial amino acid sequence, and isolation of cDNA clones."
Hibbs M.L. , Walker I.D. , Kirszbaum L. , Peitersz G.A. , Deacon N.J. , Chambers G.W. , McKenzie I.F.C. , Hogarth P.M.
Proc. Natl. Acad. Sci. U.S.A.83:6980-6984(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 17-45
9.

"Identification, in mouse macrophages and in serum, of a soluble receptor for the Fc portion of IgG (Fc gamma R) encoded by an alternatively spliced transcript of the Fc gamma RII gene."
Tartour E. , de la Salle H. , de la Salle C. , Teillaud C. , Camoin L. , Galinha A. , Latour S. , Hanau D. , Fridman W.H. , Sautes C.
Int. Immunol.5:859-868(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF ISOFORM IIB3
tissue: Macrophage.
10.

"Fc epsilon receptor I-associated lyn-dependent phosphorylation of Fc gamma receptor IIB during negative regulation of mast cell activation."
Malbec O. , Fong D.C. , Turner M. , Tybulewicz V.L. , Cambier J.C. , Fridman W.H. , Daeron M.
J. Immunol.160:1647-1658(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION;INTERACTION WITH LYN
11.

"Mutational analysis reveals multiple distinct sites within Fc gamma receptor IIB that function in inhibitory signaling."
Fong D.C. , Brauweiler A. , Minskoff S.A. , Bruhns P. , Tamir I. , Mellman I. , Daeron M. , Cambier J.C.
J. Immunol.165:4453-4462(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-290; TYR-309 AND TYR-326

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